The 2012 NFL season is back, and here at Cappers Info, we’ll be looking at some of the best games on the docket each and every week, as we try to make the most money possible off of the NFL odds for the week. Join us on Sunday, as we make our San Francisco 49ers @ New England Patriots free picks and predictions for what should be a great clash on the gridiron.

Week 15 NFL Picks: San Francisco 49ers @ New England Patriots
Date: Sunday, December 16th, 8:20 ET
Location: Gillette Stadium, Foxboro, MA
NFL Betting Odds: New England -4.5
49ers vs. Patriots On TV: NBC

If the 49ers want to make a statement, this is the night for them to make it. They’re on the road, clear across the country, against a New England team that just blew out the squad that is most likely to be the No. 1 seed in the playoffs in the AFC. This is a tougher game for New England in our eyes though, as the Niners are able to run the ball efficiently and don’t give up on it like Houston ultimately did last week. QB Colin Kaepernick is a dynamic quarterback that could give the Patriots fits. RB Frank Gore could be in for a nice day, as he has been conserved for most of the season for moments like this one when he is truly needed. The Niners haven’t played well in this series over the years, but this is a new time with a new coach and a totally new system in place. Don’t be all that shocked if this game ends in an upset, as the 49ers have the ability to come on the road and win this game.

San Francisco 49ers @ New England Patriots Pick: San Francisco 49ers +4.5
San Francisco 49ers @ New England Patriots Score Prediction: San Francisco 24 – New England 21

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