Cardinals @ 49ers Predictions For NFL Football Week 17 Odds 12/30/12

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The Arizona Cardinals and the San Francisco 49ers are going to square off in Week 17 of the NFL betting campaign. Join us here at Cappers Info, as we make our predictions for football for what should be a great game on Sunday.

Week 17 NFL Picks: Arizona Cardinals @ San Francisco 49ers
Date: Sunday, December 30th, 4:25 ET
Location: Candlestick Park, San Francisco, CA
Week 17 Betting Odds: San Francisco -16.5
Cardinals vs. 49ers Live TV: FOX

Dare we lay 16.5 with the 49ers in this game? Of course we will! When these two teams met in the desert in October when QB John Skelton calling the shots, the 49ers won 24-3. Now, we have seen Arizona go through both Skelton and QB Ryan Lindley, and the tide turns over to QB Brian Hoyer for his first career start. Arizona’s offense just hasn’t been able to get out of its own way for the most part, and there is no reason to think that Hoyer is going to be able to do any better on the road in a game that means oh so much to the 49ers. San Francisco has to have this game if it wants to have a chance at the No. 2 seed in the NFC, and more importantly if it wants to win the NFC West and avoid having to go on the road in the first round of the playoffs. The defense allowed 76 points over the course of the last two games, and that just isn’t going to continue when push comes to shove. Go with the 49ers and lay the points for sure in a game that should never be close.

Cardinals @ 49ers Pick: San Francisco 49ers -16.5
Cardinals @ 49ers Score Prediction: San Francisco 24 – Arizona 3

Lou Palumbo is the founder and part owner of the Cappersinfo.com Sports Handicapping Community. He's been writing and posting free picks and sports handicapping strategies on the Cappersinfo forums and website for 15 years now. He enjoys handicapping just as much as he did from the very first day he built the original Cappersinfo website.

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