Free NFL Pick of the Week: Bills @ 49ers Week 5 NFL Picks 10/7/12

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NFL betting fans are running to their online sportsbooks to place their Buffalo Bills vs. San Francisco 49ers bets and predictions, and here at Cappers Info, we are making our Sunday football picks for this encounter.

Week 5 Football Picks: Buffalo Bills @ San Francisco 49ers
Date: Sunday, October 7th, 4:25 ET
Location: Candlestick Park, San Francisco, CA
NFL Betting Lines: San Francisco -10
Bills vs. 49ers On TV: CBS

The Bills are just all over the place right now. They can’t stop anyone defensively, and they just don’t have an offense that can keep up with its pace that it has been on at the start of this year. That being said, this isn’t the best scheduling spot in the world for the 49ers. This is the first of three straight home games, and it is the Giants coming to town next week. It’s hard not to be thinking about the rematch of the NFC Championship Game. San Francisco won’t get picked off in this game, but winning it by double digits is a hefty task. The Bills are a stingy team, and after last week’s horrifyingly bad showing against the Patriots in the second half, they’ll want to show what they’re made of in this game.

Bills @ 49ers Pick: Buffalo Bills +10
Buffalo @ San Francisco Score Prediction: San Francisco 23 – Buffalo 17

Lou Palumbo is the founder and part owner of the Sports Handicapping Community. He's been writing and posting free picks and sports handicapping strategies on the Cappersinfo forums and website for 15 years now. He enjoys handicapping just as much as he did from the very first day he built the original Cappersinfo website.

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